На вниманието на Общината: Паркът на Младежкия хълм загива
Вредител убива тревожно бързо дървесната растителност на Младежки хълм, а институциите, които следва да вземат мерки за спасението на парковата зона, към този момент пасуват. По-рано тази седмица за проблема със зеленината на тепето ни сигнализира стопанинът на въжения парк там Иван Деспов, а вчера наш екип бе на място, за да заснеме поредния епизод от видеоподкаста „В Капана“ на Под тепето. И да излезе с призив към еколозите от Община Пловдив да реагират по възможно най-бърз начин, тъй като проблемът нараства експоненциално, а дърветата в едно от зелените сърца на Пловдив гинат едно след друго.
„От информацията, която съм събрал до този момент от специалисти, мога да кажа, че този проблем с дърветата тук се причинява от някакъв вид корояд, дървояд, но по снимки трудно може да се каже в конкретика. Трябва да се направи експертно изследване на зоната, защото ако не вземем сега мерки животът на засегнатите от този бръмбар дървета е около година, година и половина. Освен всичко, много от проядените дървета вече са опасни и някой трябва да се погрижи за тях. По уверение на районния кмет те са описани и следва да бъдат премахнати, но явно не достига капацитетът на общината да ги обслужи. Освен това следва премахнатите дървета да бъдат подменяни“, коментира Иван Деспов в разходка около няколко от многото болни дървета на Младежкия хълм.
В последния месец той преминава курс за катерач- арборист и предлага на общината да помогне напълно безвъзмездно, за да почисти според възможностите си това, което успее. До момента Деспов е писал до всяка едно от институциите, които би следвало да вземат отношение по казуса, но отговор няма от нито една от тях.
„Надявам се все пак някой да ме потърси и затова се мъча по всякакъв начин да дам гласност на ситуацията тук. Не съм човек, който просто посочва проблема, а съм готов активно да работя по решаването му с лични сили и средства. Защото паркът погива. Това е следствие от цялостното ни отношение към тепетата. Зелените тепета са не просто ресурс, те са капитал на града, но не са даденост. Нужно е да се полагат много грижи и усилия, за да ги опазим. С работа на парче и без план за действие няма да стане“, допълва Иван Деспов.
Вижте и чуйте какво се случва в парковата зона на Младежки хълм, както и призивът, който отправя видеото към Община Пловдив и всички други институции:
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References:
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Its function in selling gut health by reducing intestinal inflammation and therapeutic provides to its
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„…treatment with KPV led to earlier recovery and considerably stronger regain of body weight. Histologically, inflammatory infiltrates have been significantly lowered in KPV-treated mice, which was confirmed by the numerous discount of MPO exercise in colonic tissue after KPV treatment. This signifies that, within the absence of PepT1, proliferation of crypt epithelial cells was inhibited. Next, we used TUNEL staining to discover out the levels of apoptosis in colonic mucosa sections from WT and PepT1-KO mice.
It’s a C-terminal tripeptide of α-MSH (alpha-Melanocyte-stimulating hormone). Peptides like KPV typically act as hormones and relay info from one tissue through the blood to a different through biological messengers. Whether Or Not given orally or in the type of injections, the KPV tripeptide has the potential to deal with immune-mediated inflammatory conditions corresponding to dermatitis, bowel diseases, allergic asthma, and arthritis. In a examine examining the consequences of KPV on CAC, researchers found that KPV decreased tumor numbers and inhibited the proliferation of colonic epithelial cells in a PepT1-dependent method. This study provided critical insights into the potential of KPV as a safety measure against inflammation-induced cancer. In a examine inspecting the results of KPV on CAC, researchers found that KPV decreased tumor numbers and inhibited the proliferation of colonic epithelial cells in a PepT1-dependent method. This examine supplied important insights into the potential of KPV as a preventive measure in opposition to inflammation-induced most cancers.
Analysis protocols in this area typically combine the peptide with other therapeutic compounds to attain synergistic cardiovascular safety. Comprehensive laboratory investigations have established detailed dosing protocols for varied analysis purposes of those peptides. The optimal research concentrations differ significantly primarily based on experimental aims, cellular models, and intended outcomes. Dr. Marinov (MD, Ph.D.) is a researcher and chief assistant professor in Preventative Medicine & Public Health.
Most Cancers cells recruit CAFs, which are essential in shaping the malignant TME. Activated CAFs facilitate tumor cell growth, invasiveness, and drug resistance by depositing extracellular matrix (ECM) and secreting cytokines, chemokines, and development factors (Gascard and Tlsty, 2016). A seemingly easy therapeutic method would be to immediately goal and eliminate CAFs. Nonetheless, current research have proven that depleting αSMA (+) fibroblasts paradoxically heightens the chance of tumor invasion or migration (Özdemir et al., 2014).
Docs usually use steroids for treating pores and skin irritation, but long-term steroid use can result in serious unwanted effects. That’s where KPV stands out—it provides comparable anti-inflammatory effects with out the risks of steroids. KPV doesn’t need to work through hormone receptors like other similar peptides.
To further verify that hPepT1 transports KPV, uptake experiments have been carried out utilizing [3H]KPV. We present that, in distinction to [14C]Gly-Sar, nanomolar concentrations of [3H]KPV were efficiently transported by hPepT1 (Figure 4B). These results were confirmed by kinetic experiments showing that hPepT1 had a low Km of ~160 μM for KPV (Figure 4C).
References:
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Current developments in anti-inflammatory analysis promote combining KPV with different peptides for enhanced outcomes.
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therapeutic for difficult gut or skin situations in laboratory settings.
The alpha-MSH-derived tripeptide KPV promotes healing of colitis in mice by
inhibiting inflammatory and apoptotic pathways.
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KPV peptide is structurally derived from alpha-melanocyte-stimulating hormone
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The copper peptide stimulates Varieties I and III collagen while promoting
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In vitro competitors assays confirmed that KPV suppressed the binding of GST-Imp-α3 with
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The amount of cytokine secreted into the medium for every remedy was expressed as a fraction of the respective cellular
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pDNA3-IκBα-(S32A, S36A)-V5C have been sort items from R.
PDNA3-IκBα (G33A, L34A, D35A)-V5C was generated from pDNA3-IκBα-V5C
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A chemotherapy-induced oral mucositis rat mannequin was induced by a modified protocol based
on a previously established method.34 Briefly, SD rats received 30 mg kg−1 5-FU intraperitoneally (ip) on days 1, three and 5 before acetic acid insult.
Subsequently, on day 6, a 6 mm diameter filter paper disk
soaked with 30% acetic acid was used to create an ulcerated space on the gingival mucosa, and all of
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Възхищавам се на такива хора. Но техния глас е глас в пустиня. Жалкото е, че тук е Аграрния университет. Там са специалистите, но свикнахме да работим само по проекти с европейско финансиране. Потърсете ги. Сигурно има и такива, които ще помогнат на драго сърце.
Естествено, че никой няма да го потърси като няма далавера. Я някой комлекс от затворен тип, я някоя кръчма.
Моля Г-н Стаменов и еколога на Общината ,Вземете спешни мерки за вредителя по дърветата на Младежки хълм.
Те съхнат и се заразяват други.
Помогнете на г-н Деспов,който иска помощ
Карай е, г- н Презастрой ше опрай и тепето.. 1000 тона бетон и нема болести вече.
То за 15 години управление на ГЕРБ града загина, Вие за един парк. : Ще построим нов жилищен комплекс че там е далаверата.
Г-н Презастрой ще го презастрои, дървета и паркове не трябват на Пловдив
Що за глупости
Просто реалност