Инициатива за държавен институт по антични мозайки в Пловдив стигна до министъра на културата
Идеята бе разгледана на заседанието на Комисията по култура към Народното събрание в четвъртък
Гражданската инициатива, която предлага създаването на държавен институт за опазване на античните мозайки в Пловдив, получава все по-широк отзвук. Предложението е било обсъдено на вчерашното заседание на парламентарната Комисия по култура и медии, разбра репортер на Под тепето.
Припомняме, че преди 9 дни фондация „Споделени наследства“ – Пловдив внесе официално предложение до институциите за създаване на Държавен културен институт „Център за опазване и представяне на антични мозайки“ към Министерството на културата. Инициативата цели да обедини усилията на археолози, реставратори и експерти от различни институции. Пловдив е предложен за седалище на бъдещия център, тъй като именно тук се намират едни от най-добре съхранените и експонирани антични мозайки в България – в Голямата и Малката базилика, както и в редица археологически обекти, включени в кандидатурата за световното наследство на ЮНЕСКО.
По време на заседанието на Комисията по културата предложението беше представено от народния представител Костадин Костадинов, който подчерта, че липсата на специализиран държавен орган води до загуби и неефективно опазване на ценни археологически находки в различни части на страната.
Председателят на комисията Тошко Йорданов заяви, че ще потърси съдействие от Министерството на културата за започване на работен процес по идеята. Подробности вижте във видеото ТУК.
Според информация на „Под тепето“, културното ведомстово вече е запознато с предложението. То е на бюрото на министър Мариан Бачев още от 16 октомври. Предложението е внесено до председателя на 51-вото Народно събрание Наталия Киселова, чрез министър-председателя, министъра на културата и Комисията по култура и медии. Документът е с вх. № ПГ-51-533-00-85 от 10 октомври 2025 г. Копие е изпратено и до Посолството на САЩ у нас, Фондация „Америка за България“ и централата на ЮНЕСКО в Париж.
Очаква се да бъде насрочена среща с представители на гражданската фондация, инициирала инициативата. Предстои предложението да бъде разгледано и от Правната комисия в НС.
Проучването ни показва, че вече няколко от парламентарните групи са изразили неофициална подкрепа за инициативата, която според тях има потенциал да укрепи държавната политика по опазване на културното наследство.
Нещо повече – една от тях внася питане по процедурата за парламентарен контрол, с въпроси по темата: „какво се случва с целево отпуснатите 20 броя позиции за специалисти към Епископската базилика.“
Снимка на корицата: момент от процеса на реставрация на мозайките в Голямата базилика/ архив Под тепето
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It’s a fraction of the bigger peptide alpha-melanocyte-stimulating hormone (α-MSH), which is involved in skin pigmentation and immune function. KPV is of course found
within the physique and is understood for its anti-inflammatory properties, nevertheless it has a extra particular action on inflammation-related pathways that contribute to
various health circumstances. The systemic anti-inflammatory properties of KPV Peptide are pivotal in modulating immune responses, enhancing overall gut well being, and potentially addressing various gastrointestinal disorders.
By utilizing these focused delivery strategies,
you can amplify the therapeutic potential of KPV Peptide, offering promising outcomes for
a big selection of health situations. You should consider
KPV Peptide as a bioactive peptide with notable anti-inflammatory properties that has demonstrated important advantages
in various medical purposes.
A medical professional can assess an individual’s specific wants, consider their
medical historical past, and decide essentially the most applicable peptides and dosages.
One of probably the most promising developments in KPV research is
its potential to reduce irritation within the intestines.
KPV has been proven to cut back inflammatory cell
infiltration, MPO activity (a marker for inflammation), and enhance overall tissue well being.
Mice given KPV peptide suplement also recovered extra rapidly and
gained more weight than mice given a placebo, showing its potential to deal
with gut-based irritation.
Our workers is made up of skilled professionals who’re dedicated to
helping you achieve your objectives whereas providing the
very best high quality care. KPV is doubtless one of the
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We’re so excited to be bringing Peptide Therapy to our neighborhood, and we have seen first-hand how peptides can invoke life-enhancing results.
You can acquire any of our peptides by booking in a session with our Integrative and
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The gut actively contributes to the regulation of all different organs inside your physique.
The time period „second brain“ is incessantly used to explain the gut, and for good cause.
Most of the analysis involved is concentrating on the remedy of IBD (irritable
bowel disease) where outcomes have been very positive.
KPV is proven to be safe when administered orally, subcutaneously and topically.
KPV is a naturally derived peptide with none notable side effects.
Analysis has proven that KPV presents a number of advantages that velocity wound therapeutic, reduce
an infection and battle irritation.
Any individual contemplating peptide remedy should seek
the guidance of with a certified healthcare supplier before use.
The peptide works by enhancing fibroblast migration and boosting collagen manufacturing.
These actions help repair delicate tissue via multiple mobile pathways while exhibiting potent anti-inflammatory effects(1).
It works by inhibiting proinflammatory cytokines and
modulating inflammatory pathways, decreasing
inflammation without suppressing the immune system.
In some rare instances, people might expertise allergic reactions to peptide remedy, although
that is uncommon. As extra analysis is carried out, KPV peptide continues to show
a positive safety profile, making it a promising option for managing irritation and supporting total well being.
In contrast, KPV peptide targets the precise proinflammatory mechanisms involved in autoimmune flare-ups,
lowering irritation without compromising the immune system
as an entire.
By regulation, any type of bodily introduction of this product into humans or
animals is strictly prohibited. It ought to only be dealt with
by professionals who are licensed and certified.
This product is neither a drug, food, nor cosmetic, and must not be misrepresented, misused, or mislabeled as
such. „..decision of irritation is additional essential to stop the development of a chronic inflammatory process that lastly could lead to hypertrophic scar and keloid formation (v. i.).
It has been discovered that KPV Peptide can effectively modulate the secretion of pro-inflammatory cytokines, which play a major role within the inflammatory alterations seen in IBD. Research have proven that this peptide remedy can enhance the repair of broken mucosal tissues within the colon, resulting in improved medical outcomes for individuals affected by IBD. The capacity of KPV Peptide to influence varied mobile processes, such as apoptosis and cell proliferation, additional underscores its potential as a useful tool within the management of IBD.
Research exhibits KPV accelerates wound healing, reduces infection, and minimizes scarring. In this article, we will take an in depth look at the KPV peptide, a tripeptide fragment of the α-melanocyte stimulating hormone. We will explore its anti-inflammatory, antimicrobial, antiviral, and cardiovascular benefits, and talk about the necessity for additional research on its potential unwanted side effects. This info is designed for researchers, clinicians, and individuals thinking about peptide science.
The links I’m giving are to the specific merchandise I use, you’ll find a way to search VitaStream for lingual or combo products. Sublingual peptides are absorbed immediately through the mucous membrane of the mouth, which promotes sooner penetration of peptides and accelerates their motion. In this research, Vasoactive Intestinal Polypeptide Performs a Key Position within the Microbial-Neuroimmune Control of Intestinal Motility – ScienceDirect, they showed it could treat both IBS-C and IBS-D. However, for people who must foster a Th2 response, it might be difficult to search out treatments and VIP is an option.
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Anyway for the previous week I’ve been having alot of head stress and neck tightness
that appears to be from sympathetic overdrive. My physician gave me propranolol from months in the
past but I only took it as soon as however didn’t notice
much. Yesterday after taking 10 mg, it was the worst flair I even have had in in all probability a year.
KPV is an rising peptide in irritation and wound therapeutic
analysis, offering potential functions in gut well
being, immune modulation, and tissue regeneration. Not Like different peptides commonly studied for therapeutic and tissue restore, KPV stands out for
its ability to control inflammatory pathways with out suppressing immune
function. Its interplay with melanocortin receptors (MC1R
and MC3R) has led to rising curiosity in its role in autoimmune research, epithelial therapeutic, and chronic inflammatory situations.
KPV is a small peptide consisting of simply three amino acids, lysine-proline-valine.
It’s a fraction of the bigger peptide alpha-melanocyte-stimulating hormone (α-MSH), which is
involved in pores and skin pigmentation and immune operate.
KPV is of course found in the body and is known for its anti-inflammatory properties, however it has a more specific
motion on inflammation-related pathways that contribute to numerous health conditions.
During the final month I really have been capable of work and I’ve seen my signs have truly been fairly low.
Research have additionally demonstrated α-MSH’s
immunomodulating and anti-inflammatory effects. KPV peptide’s anti-inflammatory results are notably notable
as a end result of it instantly influences processes contained in the cell.
The small molecular dimension of KPV and α‐MSH allows them to enter the cell and interact with
inflammatory signalling molecules. KPV is a potent anti-inflammatory peptide that can help many circumstances.
Most of the research involved is focusing on the remedy of IBD (irritable bowel disease)
where results have been very optimistic.
Finding a stability between an effective dose
and one which produces too much die off is key if you
have yeast or bacterial overgrowth. Die off symptoms occur
if you kill yeast or micro organism more shortly than your body can get rid of the dead toxins.
Around week 3, we have been in a position to area it out more without having
GI points when eating snacks in between doses. When we started, I divided our total into about 5 doses all through day.
The protocol gets its name from the visible pores and skin improvements many users report within 2 to 3 weeks.
The benefits prolong far beyond cosmetic modifications to incorporate sooner harm
restoration, decreased irritation, and higher total healing capacity.
KPV, on one hand is a naturally occurring tri-peptide and is shaped by
alpha melanocyte stimulating hormone (alpha-MSH)as in comparability with TB-500 which is synthetically made.
Each these peptides are confirmed to accelerate
wound therapeutic, and act as an anti-inflammatory agent.
Due to its pleiotropic results on the physique, the standard administration of KPV
peptide with out stacking is adequate to reduce inflammation and for the remedy
of wounds. For the treatment of different inflammatory illnesses, such
as Crohn’s disease, ulcerative colitis, and irritable bowel syndrome, KPV could be administered
orally.
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Mould Sickness is a recognised illness with over 35 peer-reviewed
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Mold Toxicity or Persistent Inflammatory Response
Syndrome (CIRS), refers to a set of health issues that can happen when an individual
is exposed to mold and its mycotoxins. Insulin was the primary peptide ever found and is utilized by
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Research have proven it’s effective enough to reverse injury from a heart assault.
Peptides and bioregulators get to work immediately – lots of them bringing changes shortly after taking the first dose.
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Integrative Peptide’s KPV is a naturally occurring isomer –
acetylated and amidated to extend its stability, bioavailability, and effectiveness.
Because KPV concurrently helps heal the gut, in our expertise, the die off is
minimal compared to different strategies of treating yeast
or micro organism. As A End Result Of die off can create an acidic setting,
some people who are vulnerable to acid reflux will expertise
it when taking KPV.
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Tesamorelin has been proven to be helpful in non-alcoholic fatty liver illness.
It can reach maximum insulin-like growth issue 1 (IGF-1) levels
in 2 weeks.Ipamorelin is a development hormone releasing peptide.
The combination of a growth hormone releasing peptide and growth hormone releasing hormone creates a synergistic impact that’s about 7X more effective than utilizing
either alone. GHK-cu/Argireline/LeuphasylThis mixture of peptides repairs pores and skin and reduces fantastic lines and wrinkles.
In conclusion, KPV Peptide has proven nice promise in lowering persistent inflammation and probably treating inflammatory bowel disease.
In one research, KPV was tested on murine models of inflammatory bowel illness.
The outcomes confirmed that therapy with KPV led to earlier recovery and considerably stronger regain of physique weight.
Whereas BPC-157 reveals therapeutic potential, its safety profile and long-term results
on most cancers patients are nonetheless being investigated.
Researchers are exploring the optimum dosage and administration methods to maximize efficacy
with out compromising safety. In fielding questions recently from sufferers and physician colleagues about peptides,
I was prompted to look into the sector at extra depth.
Generally we need to additionally improve GI transit at the smooth muscle level (by utilizing
the serotonin precursor 5-HTP for example.) As mentioned, hormones have to be normalized as nicely.
This action stops proinflammatory mechanisms in both intestinal epithelial cells and immune
cells. Furthermore, KPV can immediately interact with immune cells to reduce back inflammation, showcasing its efficacy in addressing gut issues
similar to ulcerative colitis and inflammatory bowel illnesses.
In research, KPV has been proven to effectively cut back irritation referring to
colitis, tumors, and asthma through numerous mechanisms.
In this experiment, mice with induced ear swelling as a result of pores and skin rashes and dermatitis were divided into two
teams. One group acquired an irritant to induce ear swelling followed by publicity
to KPV peptide, whereas the opposite group obtained the irritant adopted by
α-MSH. After 24 hours, each teams showed related
improvement in lowering ear swelling. After two weeks,
researchers ceased publicity to each compounds and continued presenting solely the irritant.
The anti-inflammatory impact of KPV is mediated through the transporter PepT1.
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With KPV topical cream there’s a possibility that the infectious pathogens might be eradicated.
This web page could comprise delicate or grownup content that’s not for everybody.
In conclusion, KPV is a potent anti-inflammatory agent that works by lowering inflammation in quite so much of completely different disease states.
Since the expression of hPepT1 is increased in Inflammatory Bowel Illness, its transport exercise could
possibly be a potential target for anti-inflammatory therapies.
We’re excited to introduce you to the benefits of peptide remedy, including the KPV Peptide.
After a further series of washes, 1μg of protein obtained from HBE cells expressing
FLAG-p65RelA was added to every well together with KPV at concentrations starting from zero.01→30μg.ml-1.
Plates were incubated in a single day at 4°C and
then washed as before in TBST. Every nicely was
then incubated with HRP-conjugated mouse anti-FLAG IgG for 1h
at room temperature followed by 3 last washes in TBST. The quantity of p65RelA sure to the goal protein coating the nicely was visualised by adding TMB reagent
(Sigma-Aldrich) and quantified by measuring absorbance at
450nm with background correction at 595nm.
Cells were grown in 16-well coverslips for 3h in serum free medium
containing 0-10μg.ml-1 KPV with or without TNFα (5ng.ml-1).
At the 3h time level, the medium was replaced with similar medium containing 10μM 5-bromo-2’-deoxyuridine (BrdU).
Cells had been allowed to incorporate the BrdU for half-hour after which they had been mounted, the DNA was
denatured, then probed utilizing 2μg.ml-1 anti-BrdU-Fluorescein antibody (Roche).
This product is not supposed to diagnose, deal with, treatment, or stop any illness.
KPV Extremely is a peppermint-flavored oral spray containing 500
mcg of a tripeptide fragment derived from α-melanocyte-stimulating hormone (α-MSH).
Designed in a handy liquid format, KPV Ultra provides a
practical alternative to capsule or injection-based peptide supply.
Moreover, analysis efforts have centered on leveraging M2pep for the targeted supply
of CSF-1R siRNA (Sun et al., 2023b).
Research have shown that BPC-157 might have potential anti-cancer
properties by inhibiting the growth of cancer cells and selling apoptosis, which might
be a game-changer in cancer therapy. The proof base for use of those medication, both for off-label indications or as non-approved
medicine, is wanting. There is a chance that peptides in addition to GLP-1s will ultimately
be demonstrated to supply well being consequence advantages as seen in rodent pre-clinical fashions.
It decreases the inflammatory response by inhibiting proinflammatory cytokine (molecule) synthesis and secretion. Research involving immortalized human bronchial
epithelial cells demonstrated that KPV suppresses inflammation by inhibiting NFκB signaling, a key regulator in inflammatory processes.
The peptide’s impact includes nuclear import and stabilization of IκBα, which
prevents NFκB from translocating to the nucleus and initiating inflammation. This signifies a potential therapeutic role for KPV in respiratory inflammatory ailments like asthma [R].
KPV (lysine-proline-valine) is the C-terminal finish of a more outstanding
melanocortin peptide hormone called alpha-melanocyte-stimulating hormone (α-MSH), produced naturally
in the body. A melanocortin receptor agonist, α-MSH, is synthesized within the pituitary gland of most vertebrates and
is answerable for regulating vitality stability.
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