Инициатива за държавен институт по антични мозайки в Пловдив стигна до министъра на културата
Идеята бе разгледана на заседанието на Комисията по култура към Народното събрание в четвъртък
Гражданската инициатива, която предлага създаването на държавен институт за опазване на античните мозайки в Пловдив, получава все по-широк отзвук. Предложението е било обсъдено на вчерашното заседание на парламентарната Комисия по култура и медии, разбра репортер на Под тепето.
Припомняме, че преди 9 дни фондация „Споделени наследства“ – Пловдив внесе официално предложение до институциите за създаване на Държавен културен институт „Център за опазване и представяне на антични мозайки“ към Министерството на културата. Инициативата цели да обедини усилията на археолози, реставратори и експерти от различни институции. Пловдив е предложен за седалище на бъдещия център, тъй като именно тук се намират едни от най-добре съхранените и експонирани антични мозайки в България – в Голямата и Малката базилика, както и в редица археологически обекти, включени в кандидатурата за световното наследство на ЮНЕСКО.
По време на заседанието на Комисията по културата предложението беше представено от народния представител Костадин Костадинов, който подчерта, че липсата на специализиран държавен орган води до загуби и неефективно опазване на ценни археологически находки в различни части на страната.
Председателят на комисията Тошко Йорданов заяви, че ще потърси съдействие от Министерството на културата за започване на работен процес по идеята. Подробности вижте във видеото ТУК.
Според информация на „Под тепето“, културното ведомстово вече е запознато с предложението. То е на бюрото на министър Мариан Бачев още от 16 октомври. Предложението е внесено до председателя на 51-вото Народно събрание Наталия Киселова, чрез министър-председателя, министъра на културата и Комисията по култура и медии. Документът е с вх. № ПГ-51-533-00-85 от 10 октомври 2025 г. Копие е изпратено и до Посолството на САЩ у нас, Фондация „Америка за България“ и централата на ЮНЕСКО в Париж.
Очаква се да бъде насрочена среща с представители на гражданската фондация, инициирала инициативата. Предстои предложението да бъде разгледано и от Правната комисия в НС.
Проучването ни показва, че вече няколко от парламентарните групи са изразили неофициална подкрепа за инициативата, която според тях има потенциал да укрепи държавната политика по опазване на културното наследство.
Нещо повече – една от тях внася питане по процедурата за парламентарен контрол, с въпроси по темата: „какво се случва с целево отпуснатите 20 броя позиции за специалисти към Епископската базилика.“
Снимка на корицата: момент от процеса на реставрация на мозайките в Голямата базилика/ архив Под тепето
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Die off symptoms happen when you kill yeast or bacteria extra shortly than your
body can eliminate the dead toxins. Round week three,
we were capable of house it out extra with out having GI points when consuming snacks
in between doses. You don’t have to do this however no less than 3x would be higher than suddenly.
A problem with utilizing some peptides can be their brief half lives and unknown signaling
period. I was so impressed with KPV I started to research what other peptides we’d try.
KPV’s focused mechanisms allow it to behave as a molecular multitasker, soothing inflammation, combating pathogens
and strengthening immune harmony.
The potent anti-inflammatory properties of KPV are caused immediately contained in the cells, the place it is ready to suppress NFκB.
It does this by accumulating within the nucleus and
competitively inhibiting the interaction between p65RelA and
Imp-α3, which is responsible for the formation of NFκB. KPV is a naturally occurring tri-peptide that consists of Lysine, Proline, and Valine.
KPV Ultra Oral Spray delivers 500 mcg of the lively bioregulator fragment of α-Melanocyte Stimulating Hormone (α-MSH)—one of
the body’s most powerful regulators of immune stability and mast cell
operate. They could additionally be taken with or without food, depending on individual preferences.
For particular guidance regarding timing or mixtures with meals, consult your healthcare
supplier. From autoimmune flares to leaky intestine and inflammatory pores and skin problems, KPV offers a strong yet gentle
method to restore immune steadiness and cut back persistent irritation at the root.
Schedule your consultation right now with our Tulsa-based team at Revolution Health & Wellness and take the first step toward true regenerative therapeutic.
To explore your options, go to our peptide catalog at RevolutionHealth.org or schedule a consultation with considered one of our functional medication providers.
Peptides are brief chains of amino acids that
act as signaling molecules within the body.
They regulate numerous biological processes—immunity, tissue regeneration, hormone signaling, and irritation control among
them. KPV peptide can be taken orally, utilized topically, or
injected, depending on the condition being treated.
Most users observe a cycle lasting 4-8 weeks,
with day by day dosages depending on individual well being objectives and the severity of irritation. After the cycle, a break
is normally beneficial before beginning a brand new course to allow the body to regulate.
KPV is a naturally occurring tri-peptide which is discovered
within the alpha melanocyte secreting hormone. It is a potent anti-inflammatory substance which suppresses NFκB, a proinflammatory cytokine and therefore
inhibits irritation and the drastic results which are
adopted by it. KPV additionally exerts its antimicrobial properties thus
defending the body from opportunistic infections.
It modulates collagen deposition and thus is ready to scale back scarring whereas dashing up the method of wound therapeutic.
KPV’s advantages extend to gut well being, where it assists in alleviating inflammation related to circumstances like inflammatory bowel diseases and irritable bowel syndrome.
I began taking it for pelvic pain like UTI however haven’t any UTI and intestine issues
as a result of excessive doses of antibiotics and the pelvic ache was gone after second day of
500 m capsule. The main operate of both these peptides is to
advertise wound healing but just like Pentosan, the origin of both the peptides
differ. Each these peptides are proven to accelerate wound therapeutic,
and act as an anti-inflammatory agent.
All products are offered for research, laboratory, or analytical purposes solely, and usually are not for human consumption.Peptide Hub is a
chemical supplier. Peptide Hub just isn’t a compounding pharmacy or chemical compounding facility as
defined beneath 503A of the Federal Food, Drug, and Beauty Act.
Peptide Hub is not an outsourcing facility as defined underneath 503B of the Federal Meals, Drug, and
Cosmetic Act.
This is an artificial peptide composed of 15 amino acids and has
been referenced in scientific literature. People interested in studying more are inspired to seek the
assistance of publicly available research or a certified veterinary skilled.
There is always the prospect of potential interactions
with other medications an individual could also be taking.
It is essential to work with an experienced Functional Medication practitioner when taking KPV or any
other peptides. Our clinic has intensive expertise with
peptides and may help you with KPV or different peptides.
KPV was sufficient to decrease the irritation of carcinogenesis (Viennois E,
2016). Using KPV before the event of colon most cancers could be a preventive way to cease
colonic carcinogenesis earlier than it begins (Viennois E, 2016).
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Additionally bear in mind that sufficient progesterone is critical,
as is enough thyroid hormone for optimum gut motility.
Gut motility depends on a healed intestine which
includes a healed smooth muscle propulsive layer.
If you continually „feel stressed“, likelihood is superb that you have a excessive cortisol stage.
Excessive cortisol-apart from every little thing else
we’re discussing-can trigger the breakdown of your GI lining.
It does this by slowing down both GI motility (peristalsis)
and the process of digestion. When this occurs, some individuals experience reflux, or „heartburn“ whereas
others have absolutely no signs. This results in the next focus of poisonous metabolites which then whittle away at your gut lining.
These treatments can improve oxidative stress, which can be dangerous to people with
G6PD deficiency, potentially leading to hemolytic anemia.
It works by inhibiting proinflammatory cytokines and modulating inflammatory pathways,
reducing inflammation without suppressing the immune system.
One thrilling space of research involves the development of recent delivery strategies, corresponding to KPV-loaded nanoparticles (NPs).
This technology could significantly enhance the therapeutic efficacy of KPV by enhancing its bioavailability and permitting for extra targeted treatment.
Nanoparticles may help deliver KPV peptide directly to infected tissues or areas of the physique that
need therapeutic, reducing the quantity of the peptide that is metabolized earlier than it can take impact.
Topical application of KPV peptide is right for pores and skin situations or
localized wounds. In this case, the peptide is utilized on to the affected space, allowing it to focus on irritation and promote healing on the website of the wound.
This study supplied crucial insights into the potential
of KPV as a preventive measure against inflammation-induced cancer.
Since BPC-157 and TB-500 both target tissue regeneration,
they are usually studied collectively for their potential
synergistic results on wound therapeutic and damage restoration. You will not discover massive randomized controlled trials
in aggressive athletes. You will find a consistent preclinical
story across intestine, skin, and immune fashions the place KPV peptide
reduces inflammatory signaling, preserves barrier integrity,
and speeds epithelial restore.
And given the absence of melanocyte stimulation (i.e.
skin pigmentation effects), researchers believed they lastly discovered what they
were looking for. Get ready to find a model new Golden Age treatment
only a few peptide physicians even know about in 2021.
It’s not every single day you get to be on the forefront of a brand new therapeutic peptide being launched into the world.
Given its strong anti-inflammatory properties, KPV could be investigated
for its potential advantages in different inflammatory and
autoimmune diseases past the gastrointestinal tract.
In a examine centered on UC, mice treated with HA-KPV-NPs showed
vital improvements in mucosal therapeutic and a discount
in pro-inflammatory cytokine levels. This study utilized electrical impedance sensing (ECIS) expertise to measure the healing of wounded epithelial layers, demonstrating the effectiveness of HA-KPV-NPs in enhancing restoration. A wholesome gut is
crucial for amino acid uptake, protein digestion, and micronutrient assimilation.
Caco2-BBE and HT29-Cl.19A cells were grown in DMEM supplemented with 14 mM NaHCO3, 10% FBS, and penicillin/streptomycin (Invitrogen, Grand Island,
NY). Jurkat cells have been grown in RPMI 1640 (Invitrogen) supplemented with 10% FBS.
If you ever get severe symptoms—like facial swelling, chest
ache, or huge rashes—get help right away.
This hardly ever happens, however you wish to be prepared, particularly if you’ve had reactions to supplements earlier than. Most speak about sooner healing in the occasion that
they get bumps or pulls, unimaginable to avoid when you prepare at
excessive ranges. You might get pleasure from higher joint consolation, especially with
more volume or heavy units each week.
This approach is advantageous because it enhances drug absorption and ensures environment friendly delivery of
KPV for effective therapeutic outcomes. These assets are glorious starting points for anybody keen on understanding KPV’s promising capabilities and potential
future applications in well being and wellness.
Amongst the developments, (CKPV)2 stands out due to its unique structure.
It consists of two KPV items joined by a cysteine-cysteine bridge, known as a loop peptide.
This design has demonstrated exceptional efficacy in combating drug-resistant fungal strains similar to C.
This approach is advantageous as it enhances drug absorption and ensures efficient delivery
of KPV for efficient therapeutic outcomes.
KPV stands out because it can be applied orally, topically, or systemically—making it one of the versatile research peptides in the inflammation and restore category.
→ Antimicrobial effectsResearch suggests KPV could exert delicate antimicrobial
actions, additional supporting tissue healing by limiting pathogen-driven inflammation. KPV isn’t about shutting the immune system off—it’s about educating it when to calm down,
making it some of the thrilling peptides within the inflammation and restoration area.
It just isn’t approved for human consumption or to diagnose, treat,
remedy, or forestall any illness. Always seek the guidance of a licensed healthcare supplier earlier than starting
any research protocol.
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The persistent irritation that happens within the brain in the course of the
progression of these illnesses results in neuronal damage and
cognitive decline. KPV peptide’s ability to reduce systemic
irritation may provide a way to sluggish the progression of those
conditions and protect neurological function. What makes the KPV peptide unique is its capability to modulate inflammatory pathways with out inflicting
immunosuppression. From soothing inflammatory bowel disease (IBD) and intestine issues to
rushing up wound healing, it’s obtained your again. In this information, I’ll dive
into all things KPV—how it works, what it does, and
the highest products out there. Proper now, analysis on KPV supports its security for muscle restoration and gut well being.
If you need easy, mild help for therapeutic, it’s wanting promising.
However, sure kinds of artificial peptides considered linked to muscle progress, known as development hormone secretagogues (GHS), may be unlawful and unsafe.
For occasion, they may scale back your body’s
sensitivity to insulin and improve your blood sugar. In addition, if you are competing in an athletic
competitors, all GHS supplements are on the World Anti-Doping Company’s banned record.
One Other examine investigated the anti-inflammatory effects of
KPV in TNBS-induced colitis models. The outcomes showed that KPV significantly lowered weight reduction, MPO activity, and
pro-inflammatory cytokine ranges within the colon.
Studies appear to show that KPV stimulates the
manufacturing of immune system cells. A Quantity Of research have discovered that KPV can lower physique temperature and prevent fever.
In one other research, KPV helped cut back inflammatory eye illness signs and considerably reduced the inflammatory substances resulting from the ailments.
Whereas the analysis surrounding the KPV peptide is not vast, it offers
compelling insights into its potential well being advantages.
A search on PubMed indicates that about 70 studies had been conducted between 1973 and 2021.
The main knowledge stems from in vivo and in vitro research, animal research, and small-scale human trials.
At TRT MD, KPV is used as part of a complete therapy plan for
individuals dealing with irritation, autoimmune circumstances, and healing-related points.
In addition to its anti-inflammatory effects, KPV also has antimicrobial properties, making it efficient
towards pathogens like S. In Distinction To Alpha-Melanocyte-stimulating hormone (Alpha-MSH), KPV
does not trigger pores and skin pigmentation, making it a safer alternative for patients
concerned about skin-related side effects.
Whether used for healing, reducing irritation,
or strengthening the immune system, KPV offers a multi-faceted strategy to
enhancing total well being and well-being.
After making an attempt a number of peptides individually, I found that solely the synergistic combo of BPC-157 and TB-4
labored on my connective tissue points. I have only injected subcutaneously, and my hip, which
used to pop misplaced, doesn’t anymore. Additionally, I
even have read that it doesn’t matter where you inject, although
I’ve had one of the best results when injecting close to
the world.
Turning to the PDES inhibitor medication like Viagra or Cialis is helpful just for some males
but not for women. The most typical complaints are of erectile dysfunction and lack of libido.
In fact, in the older pool of premenopausal ladies, approximately 6 million suffer
from hypoactive sexual need. However if I had been making a guess on this, my wager could be that that figure is far, a lot greater.
And for that group of girls the melanocortin peptide PT-141, must be given a strive.
One space of well being that some are reluctant to discuss
however is an issue in an enormous proportion of adults of both sexes, is that of dysfunctional sexual health.
In some instances, intravenous (IV) administration of KPV peptide
could also be used, significantly in more extreme cases of persistent inflammation or immune system problems.
IV administration ensures the peptide reaches
the bloodstream instantly, providing rapid relief from irritation. By decreasing the
chance of infection, KPV peptide enhances the body’s
capability to heal wounds and recover from
inflammatory situations more quickly and effectively.
Derived from a hormone your physique already makes, KPV is catching consideration for its capacity to deal with ache in an entire
new means. Let’s discover what KPV is, the way it works, and why it may be the
solution you’ve been in search of. Given its robust anti-inflammatory properties,
KPV could be investigated for its potential advantages
in different inflammatory and autoimmune ailments beyond the gastrointestinal tract.
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By Way Of their signaling capabilities, peptides can regulate
gene expression, protein synthesis, and influence DNA
interactions and epigenetic mechanisms. Not only can it diminish irritation, it also has
antimicrobial effects against pathogens, micro organism, candida,
and mold. KPV peptide is the amino acids Lysine-Proline-Valine joined collectively by peptide bonds.
When it involves sourcing high-quality KPV peptides for
analysis purposes, we stand out as a trusted supplier.
We emphasize rigorous high quality assurance protocols to ensure the
purity of our KPV peptides, with purity testing performed for every batch.
One of the most well-studied advantages of KPV is its anti-inflammatory properties.
KPV inactivates inflammatory pathways inside cells by interacting immediately with inflammatory signaling molecules.
It’s particularly effective at treating inflammation in immune cells and epithelial cells.
In studies, KPV has been shown to effectively
reduce inflammation referring to colitis, tumors, and bronchial
asthma by way of numerous mechanisms. Specifically, KPV
significantly decreases irritation in colitis by inhibiting
proinflammatory cytokine synthesis and secretion.
Timing enhances their effectiveness for muscle growth and restoration. Like some other peptides, KPV peptide can speed the therapeutic of wounds.
Plus, since it fights inflammation, reduces an infection, and has antimicrobial results, it could produce better
beauty results in wounds. KPV treatment can present smaller-than-normal scars, a lesser inflammatory
response, and lowered scar prominence as a end result of it
modulates collagen metabolism. KPV has also been shown to reduce back
the inflammation that often results in keloids or hypertrophic scars.
KPV therapy can provide smaller-than-normal scars, a lesser inflammatory response, and decreased scar prominence because it modulates
collagen metabolism. KPV has additionally been shown to
reduce the irritation that normally results in keloids or hypertrophic scars.
KPV has been proven to lower the expression of key pro-inflammatory cytokines similar to IL-6,
IL-12, IL-1β, TNF-α, and IFN-γ. This impact was observed each in vitro and in vivo, indicating its potential as a potent anti-inflammatory agent.
Notably, KPV did not increase the levels of anti-inflammatory cytokines
like IL-10, suggesting that its major mechanism is the discount of pro-inflammatory alerts.
Its potential to reduce the production of inflammatory
cytokines positions KPV as a compound of interest for studying inflammatory responses.
The antimicrobial properties of KPV peptide add one other layer of profit to its analysis profile.
Research suggests that KPV exhibits antimicrobial properties, which might help
in stopping infections through the wound healing course of.
The optimum sequence of amino acids for antimicrobial impression is
KPV, which is suggested to assist in hindering the growth of micro
organism by disrupting their cell membranes. Peptides enhance
skin regeneration and tissue healing, due to this fact remodeling
medical aesthetics. Nonetheless, understanding potential adverse
effects—in both topical and injectable forms—is vital.
Environmental triggers, in addition to extended sun exposure because of whatever causes,
could compromise the well being of your pores and skin, and it could trigger skin/cosmetic injury that may be beyond repair.
There is proscribed data on drug interactions, so consult a healthcare skilled before use.
While the BPC-157 Peptide side effect isn’t
completely studied to determine thorough details, BPC-157
and different peptide-containing supplements are in danger for inflicting this
aspect effect. Involving receptors means they shrink towards the
within and are unavailable for binding onto the substrate protein.
BPC-157 has been reported to have mild effects of fluid retention on the body.
This could also be due to fluctuations in glomerular filtration rate which in flip alters the
set level for the quantity of water to be retained and that to
be expelled from the body. There may be edema and the swelling would possibly manifest in the ankles and the arms.
Researchers are exploring varied analogs and progressive supply methods to
maximize KPV’s potential. Analogs like KdPT and (CKPV)2 have proven superior anti-inflammatory and anti-fungal activity.
Amongst the developments, (CKPV)2 stands out because of its unique construction. It consists of two KPV items joined
by a cysteine-cysteine bridge, often identified as a
loop peptide. This design has demonstrated distinctive efficacy in combating drug-resistant
fungal strains such as C. An extensive useful resource that has
gathered numerous research on the benefits of KPV is a group derived from α-MSH research.
The potent anti-inflammatory properties of KPV are caused immediately contained in the cells, the place
it is able to suppress NFκB. It does this by accumulating within the nucleus and competitively inhibiting the interaction between p65RelA and Imp-α3, which is
liable for the formation of NFκB. „A particular formulation of porcine derived peptide mix brings the best standard in high quality and security to assist cognitive health and well-being. Every peptide’s message is set by its particular sequence of amino acids.
We know this because of a 2008 systematic evaluate where 37 animal studies compiled between 1981 and 2008 showcase the consistent anti-inflammatory results of α-MSH. Many more research later, KPV was concluded to „exert a similar or even more pronounced anti‐inflammatory exercise as full‐length α‐MSH“ (Source). Scientists rightly wanted a molecule that handled chronic irritation – and solely inflammation – without having other unwanted effects. It’s the smallest peptide I’ve seen but its dimension just isn’t a mirrored image of its powerful health benefits… ESPECIALLY for the chronically inflamed. Hear to your body, modify your use, and talk to a health pro for peace of thoughts.
It can also be safely used by sufferers who have been identified with autoimmune diseases corresponding to psoriasis, ulcerative colitis, rheumatoid arthritis, and different inflammatory conditions. Zero serious unwanted effects present in animal or human studies – even at high doses. Your liver handles it simply since it’s just three natural amino acids.
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